Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
2005-11-10
Physica A 343, 359-375 (2004).
Physics
Condensed Matter
Soft Condensed Matter
Scientific paper
10.1016/j.physa.2004.06.062
We present a thermodynamically consistent mesoscopic model of protein adsorption at liquid-solid interfaces. First describing the equilibrium state under varying protein concentration of the solution and binding conditions, we predict a non-trivial (non- monotonic) dependence of the experimentally observable properties of the adsorbed layer (such as the surface density and surface coverage) on these parameters. We subsequently proceed to develop a dynamical model consistent with the equilibrium description, which qualitatively reproduces known experimental phenomena and offers a promising way of studying the exchange of the adsorbed proteins by the proteins of the solution.
Derenyi Imre
Szollosi Gergely J.
Voros Janos
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