Noise-induced metastability in biochemical networks

Details Noise-induced metastability in biochemical networks Noise-induced metastability in biochemical networks

2012-04-19

arxiv.org/abs/1204.4341v1

Physics

Condensed Matter

Statistical Mechanics

4 pages, 3 figures

Scientific paper

Intra-cellular biochemical reactions exhibit a rich dynamical phenomenology which cannot be explained within the framework of mean-field rate equations and additive noise. Here, we show that the presence of metastable states and radically different timescales are general features of a broad class of autocatalyic reaction networks, and moreover, that this fact may be exploited to gain analytical results. The latter point is demonstrated by a treatment of the paradigmatic Togashi-Kaneko reaction, which has resisted theoretical analysis for the last decade.

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