Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
2008-08-07
Phys. Rev. E vol. 80, 051912 (2009)
Physics
Condensed Matter
Soft Condensed Matter
11 pages, 11 figures. Major rewrite including improved justification of the model and a finite size scaling
Scientific paper
10.1103/PhysRevE.80.051912
We discuss the physics of embolic stroke using a minimal model of emboli moving through the cerebral arteries. Our model of the blood flow network consists of a bifurcating tree, into which we introduce particles (emboli) that halt flow on reaching a node of similar size. Flow is weighted away from blocked arteries, inducing an effective interaction between emboli. We justify the form of the flow weighting using a steady flow (Poiseuille) analysis and a more complicated nonlinear analysis. We discuss free flowing and heavily congested limits and examine the transition from free flow to congestion using numerics. The correlation time is found to increase significantly at a critical value, and a finite size scaling is carried out. An order parameter for non-equilibrium critical behavior is identified as the overlap of blockages' flow shadows. Our work shows embolic stroke to be a feature of the cerebral blood flow network on the verge of a phase transition.
Chung E. M. L.
Hague J. P.
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