Modeling Translation in Protein Synthesis with TASEP: A Tutorial and Recent Developments

Details Modeling Translation in Protein Synthesis with TASEP: A Tutorial and Recent Developments Modeling Translation in Protein Synthesis with TASEP: A Tutorial and Recent Developments

2011-08-16

arxiv.org/abs/1108.3312v1

Journal of Statistical Physics 2011

Physics

Condensed Matter

Statistical Mechanics

25 pages, 7 figures

Scientific paper

10.1007/s10955-011-0183-1

The phenomenon of protein synthesis has been modeled in terms of totally asymmetric simple exclusion processes (TASEP) since 1968. In this article, we provide a tutorial of the biological and mathematical aspects of this approach. We also summarize several new results, concerned with limited resources in the cell and simple estimates for the current (protein production rate) of a TASEP with inhomogeneous hopping rates, reflecting the characteristics of real genes.

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