Trna - Rrna Sequence Homologies - a Model for the Origin of a Common Ancestral Molecule and Prospects for its Reconstruction

Details Trna - Rrna Sequence Homologies - a Model for the Origin of a Common Ancestral Molecule and Prospects for its Reconstruction Trna - Rrna Sequence Homologies - a Model for the Origin of a Common Ancestral Molecule and Prospects for its Reconstruction

Dec 1984

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1984orli...14..571b&link_type=abstract

Origins of Life, Volume 14, Issue 1-4, pp. 571-578

Physics

1

Scientific paper

A model is proposed for the early evolution of the coding mechanism. A primordial RNA embodies the functions of today's nucleic acids in a single molecule. The molecule is generated by successive rounds of self-priming and-templating. After proximity is assured by enclosure in a cell, the functions can be partitioned among more efficient specializel molecules. The prediction of sequence homologies in later forms prompted a search for matches between t- and r-RNAs. These are described. Their distributions offer clues to their origins. The existance of overlapping homologies indicates an approach to the reconstruction of an ancestral molecule.

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