Towards quantitative tissue absorption imaging by combining photoacoustics and acousto-optics

Details Towards quantitative tissue absorption imaging by combining photoacoustics and acousto-optics Towards quantitative tissue absorption imaging by combining photoacoustics and acousto-optics

2012-01-11

arxiv.org/abs/1201.2306v1

Physics

Optics

14 pages, 5 figures

Scientific paper

We propose a strategy for quantitative photoacoustic mapping of chromophore concentrations that can be performed purely experimentally. We exploit the possibility of acousto-optic modulation using focused ultrasound, and the principle that photons follow trajectories through a turbid medium in two directions with equal probability. A theory is presented that expresses the local absorption coefficient inside a medium in terms of noninvasively measured quantities and experimental parameters. Proof of the validity of the theory is given with Monte Carlo simulations.

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