Coupled Two-Way Clustering Analysis of Breast Cancer and Colon Cancer Gene Expression Data

Details Coupled Two-Way Clustering Analysis of Breast Cancer and Colon Cancer Gene Expression Data Coupled Two-Way Clustering Analysis of Breast Cancer and Colon Cancer Gene Expression Data

2002-06-17

arxiv.org/abs/physics/0206060v1

Bioinformatics 19, 1079 (2003).

Physics

Biological Physics

9 pages, 4 figures

Scientific paper

We present and review Coupled Two Way Clustering, a method designed to mine gene expression data. The method identifies submatrices of the total expression matrix, whose clustering analysis reveals partitions of samples (and genes) into biologically relevant classes. We demonstrate, on data from colon and breast cancer, that we are able to identify partitions that elude standard clustering analysis.

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