Fluorescent Endoscopy of Tumors in Upper Part of Gastrointestinal Tract

Details Fluorescent Endoscopy of Tumors in Upper Part of Gastrointestinal Tract Fluorescent Endoscopy of Tumors in Upper Part of Gastrointestinal Tract

Apr 2007

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2007aipc..899..467b&link_type=abstract

SIXTH INTERNATIONAL CONFERENCE OF THE BALKAN PHYSICAL UNION. AIP Conference Proceedings, Volume 899, pp. 467-468 (2007).

Physics

Optics

Optical Absorption, Magnetic Circular Dichroism, And Fluorescence Spectroscopy, Light-Emitting Devices, Non-Ionizing Radiation Equipment And Techniques, Diseases

Scientific paper

In the recent study delta-aminolevulinic acid/Protoporphyrin IX (5-ALA/PpIX) is used as fluorescent marker for dysplasia and tumor detection in esophagus and stomach. The 5-ALA is administered per os six hours before measurements at dose 20mg/kg weight. High-power light-emitting diode at 405 nm is used as an excitation source. Special opto-mechanical device is built for LED to use the light guide of standard video-endoscopic system (Olimpus Corp.). Through endoscopic instrumental channel a fiber is applied to return information about fluorescence to microspectrometer (USB4000, OceanOptics Inc.). Very good correlation between fluorescence signals and histology examination of the lesions investigated is achieved.

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