Early role during chemical evolution for cytochrome P450 in oxygen detoxification

Details Early role during chemical evolution for cytochrome P450 in oxygen detoxification Early role during chemical evolution for cytochrome P450 in oxygen detoxification

Aug 1975

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1975natur.256..509w&link_type=abstract

Nature, Volume 256, Issue 5517, pp. 509-511 (1975).

Physics

1

Scientific paper

IT is generally held that early in the evolutionary history of the Earth, when abiogenic chemicals were forming associations possessing attributes by which we now define living organisms, this planet had a reducing atmosphere. The subsequent appearance of free or molecular oxygen must have had a profound effect on such poorly specialised life forms and many would have perished. It was long assumed that the adaptive enzymatic changes of the successful forms were chiefly the elaboration of the respiratory chain enzymes, peroxidases and catalase. Research on superoxide dismutase1 has suggested that this enzyme may also have controlled oxygen toxicity in ancient living tissue. We have studied cytochrome P450, which also metabolises oxygen, and believe that this protein may possibly be more primitive than those considered previously and may even have emerged before the advent of atmospheric oxygen.

Affiliated with

Also associated with

No associations

Rating

Early role during chemical evolution for cytochrome P450 in oxygen detoxification does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Early role during chemical evolution for cytochrome P450 in oxygen detoxification, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Early role during chemical evolution for cytochrome P450 in oxygen detoxification will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-1541384