Sensitive life detection: extraction of nucleic acids sorbing to Mars analogue minerals

Details Sensitive life detection: extraction of nucleic acids sorbing to Mars analogue minerals Sensitive life detection: extraction of nucleic acids sorbing to Mars analogue minerals

Oct 2011

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2011epsc.conf..132d&link_type=abstract

EPSC-DPS Joint Meeting 2011, held 2-7 October 2011 in Nantes, France. http://meetings.copernicus.org/epsc-dps2011, p.132

Physics

Scientific paper

The main goal of space missions to Mars is to find irrefutable proof of life. Consequently, the development, evaluation and optimization of sensitive extraction and detection methods for biomarkers are of extreme importance. Our aim consisted in the optimization of sensitive extraction techniques for molecules storing hereditary information (nucleic acids such as DNA), since these are common in life forms. However, adsorption of nucleic acids to mineral matrixes and soils can generate low extraction yields. Therefore, a second aim was to determine adsorption and identify 'problematic' Mars analogue minerals. In addition, the development of a method for quantification of DNA recovery by the use of an internal control was proved to be essential, since sensitive extraction needs information on recovery.

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