Polymer-membrane interaction, conformational transitions and soft mode instabilities

Physics

Scientific paper

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Proteins, Dynamics And Conformational Changes, Membranes, Bilayers, And Vesicles

Scientific paper

The biopolymers and membranes constitute the basic structures of the biological systems in mesoscopic level. Due to flexibility combined with low dimensionality in their primary structures, they tend to be susceptible to thermal fluctuation and thus undergo conformational transitions relevant to biological functions. In this vein, I will review our recent studies of conformational transitions and instabilities in the interacting systems of a polymer and a membrane, including a semiflexible polymer on a surface, a model membrane-bound protein conformations, membrane budding and encapsulation by an adsorbed polymer, and soft mode instability of membranes. The central themes of the paper are soft matter flexibility and connectivity that can give rise to a variety of conformational change and cooperativity. .

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