What one can learn from experiments about the elusive transition state?

Details What one can learn from experiments about the elusive transition state? What one can learn from experiments about the elusive transition state?

2004-05-18

arxiv.org/abs/q-bio/0405013v1

Biology

Quantitative Biology

Biomolecules

Protein Science in press

Scientific paper

We present the results of an exact analysis of a model energy landscape of a
protein to clarify the notion of the transition state and the physical meaning
of the $\phi$ values determined in protein engineering experiments. We
benchmark our findings to various theoretical approaches proposed in the
literature for the identification and characterization of the transition state.

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