Vaccine Biotechnology by Accelerated Electron Beam and Microwave Irradiation

Details Vaccine Biotechnology by Accelerated Electron Beam and Microwave Irradiation Vaccine Biotechnology by Accelerated Electron Beam and Microwave Irradiation

Apr 2007

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2007aipc..899..769c&link_type=abstract

SIXTH INTERNATIONAL CONFERENCE OF THE BALKAN PHYSICAL UNION. AIP Conference Proceedings, Volume 899, pp. 769-769 (2007).

Biology

Quantitative Biology

Biomolecules

Effects Of Radiation And External Fields On Biomolecules, Cells And Higher Organisms, Diseases, Environmental Safety

Scientific paper

A new biotechnology for obtaining a commercial vaccine that contains either Fusobacterium necrophorum (F.n.) exotoxins inactivated by accelerated electron beam (EB) and microwave (MW) irradiation, or exotoxins isolated from F.n. cultures irradiated with EB+MW, is presented. This vaccine is designed for prophylaxis of ruminant infectious pododermatitis (IP) produced by F.n. Also, the research results concerning the effects of combined chemical adjuvant and EB+MW irradiation on F.n. immune capacity are discussed. The vaccine's efficacy will be tested in ruminant farms in which IP evolves. It is expected that this new vaccine to offer a better protection, more than 60%, which is the best presently obtained result in ruminant farms.

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