Treatment Planning with Ivis Imaging and Monte Carlo Simulation

Details Treatment Planning with Ivis Imaging and Monte Carlo Simulation Treatment Planning with Ivis Imaging and Monte Carlo Simulation

Apr 2006

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2006apsp.conf..747n&link_type=abstract

ASTROPARTICLE, PARTICLE AND SPACE PHYSICS, DETECTORS AND MEDICAL PHYSICS APPLICATIONS . Proceedings of the 9th Conference . Held

Physics

Medical Physics

Scientific paper

The vessel wall is the planned target volume in intracoronary brachytherapy. The success of the treatment is based on the need of delivering doses possibly not lower than 8 and not higher than 30 Gy.
An automatic procedure in order to acquire intravascular ultrasound images of the whole volume to be irradiated is pointed out; a motor driven pullback device, with velocity of the catheter of 0.5 and 1 mm/s allows to acquire the entire target volume of the vessel with a number of slices normally ranging from 400 to 1600.
A semiautomatic segmentation and classification of the different structures in each slice of the vessel is proposed.
The segmentation and the classification of the structures allows the calculation of their volume; this is very useful in particular for plaque volume assessment in the follow-up of the patients. A 3D analyzer tool was developed in order to visualize the walls and the lumen of the vessel. The knowledge, for each axial slice, of the source position (in the center of the catheter) and the target position (vessel walls) allows the calculation of a set of source-target distances. Given a time of irradiation, and a type of source a dose volume histogram (DVH) describing the dose distribution in the whole target can be obtained with a Monte Carlo simulation.
The whole procedure takes few minutes and then is compatible with a safe treatment of the patient, giving an important indication about the quality of the radiation treatment selected.

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