Transport by molecular motors in the presence of static defects

Details Transport by molecular motors in the presence of static defects Transport by molecular motors in the presence of static defects

2009-05-07

arxiv.org/abs/0905.0965v1

J. Stat. Phys. 135, 241-260 (2009)

Physics

Biological Physics

20 pages, latex, 7 figures, 1 table

Scientific paper

10.1007/s10955-009-9715-3

The transport by molecular motors along cytoskeletal filaments is studied theoretically in the presence of static defects. The movements of single motors are described as biased random walks along the filament as well as binding to and unbinding from the filament. Three basic types of defects are distinguished, which differ from normal filament sites only in one of the motors' transition probabilities. Both stepping defects with a reduced probability for forward steps and unbinding defects with an increased probability for motor unbinding strongly reduce the velocities and the run lengths of the motors with increasing defect density. For transport by single motors, binding defects with a reduced probability for motor binding have a relatively small effect on the transport properties. For cargo transport by motors teams, binding defects also change the effective unbinding rate of the cargo particles and are expected to have a stronger effect.

Affiliated with

Also associated with

No associations

Rating

Transport by molecular motors in the presence of static defects does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Transport by molecular motors in the presence of static defects, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transport by molecular motors in the presence of static defects will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-455387