Traffic of molecular motors: from theory to experiments

Details Traffic of molecular motors: from theory to experiments Traffic of molecular motors: from theory to experiments

2007-10-06

arxiv.org/abs/0710.1384v1

Physics

Biological Physics

Based on the oral contribution given at the Traffic and Granular Flow conference 2007 (Paris)

Scientific paper

Intracellular transport along microtubules or actin filaments, powered by molecular motors such as kinesins, dyneins or myosins, has been recently modeled using one-dimensional driven lattice gases. We discuss some generalizations of these models, that include extended particles and defects. We investigate the feasibility of single molecule experiments aiming to measure the average motor density and to locate the position of traffic jams by mean of a tracer particle. Finally, we comment on preliminary single molecule experiments performed in living cells.

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