Thermodynamics and dynamics of the formation of spherical lipidic vesicles

Details Thermodynamics and dynamics of the formation of spherical lipidic vesicles Thermodynamics and dynamics of the formation of spherical lipidic vesicles

2009-05-28

arxiv.org/abs/0905.4634v1

Physics

Biological Physics

14pgs, 6 figures, sendo to Jour. Phys. Biol

Scientific paper

We propose a free energy expression accounting for the formation of spherical vesicles from planar lipidic membranes and derive a Fokker-Planck equation for the probability distribution describing the dynamics of vesicle formation. We found that formation may occur as an activated process for small membranes and as a transport process for sufficiently large membranes. We give explicit expressions for the transition rates and the characteristic time of vesicle formation in terms of the relevant physical parameters.

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