The use of oscillatory signals in the study of genetic networks

Details The use of oscillatory signals in the study of genetic networks The use of oscillatory signals in the study of genetic networks

2005-02-23

arxiv.org/abs/q-bio/0502033v1

Biology

Quantitative Biology

Molecular Networks

46 pages, 5 figures. Submitted to PNAS on May 27th 2004. The paper is under consideration

Scientific paper

10.1073/pnas.0403790102

The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. It is found that there are important advantages in using oscillatory signals over step or impulse signals, and that the system may enter into a pure fluctuation resonance for a specific input frequency.

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