Physics – Medical Physics
Scientific paper
Jan 1997
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1997aipc..387..915f&link_type=abstract
Space technology and applications international forum (STAIF - 97). AIP Conference Proceedings, Volume 387, pp. 915-920 (1997).
Physics
Medical Physics
2
Aerospace Bio- And Medical Physics
Scientific paper
Studies conducted on two recent shuttle missions (STS-69 and STS-73) have shown that cell cycle arrest of human myeloma IM-9 cells, mediated by a purified cell regulatory sialoglycopeptide (CeReS-18), can maintain cells in a stabilized condition for several days prior to launch. In addition, when the orbiter reached the microgravity environment, the inhibition was readily reversed by a simple dilution of the concentration of the inhibitory CeReS-18. This was accomplished by the introduction of fresh culture medium, without inhibitor. The previously stabilized cell population then rapidly initiated a renewal of cell cycling. Since it has been previously shown that the ability of CeReS-18 to stabilize cell populations in a nonproliferating state was calcium ion dependent (Betz et al. 1994, Betz et al. 1995) the current studies included the use of culture medium containing either high (0.42 mM) or low (0.042 mM) calcium concentrations.
Fattaey Heideh K.
Johnson Terry C.
No associations
LandOfFree
The stabilization of cell proliferation and its reversal in the microgravity environment does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with The stabilization of cell proliferation and its reversal in the microgravity environment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and The stabilization of cell proliferation and its reversal in the microgravity environment will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-1784601