The Effects of Stacking on the Configurations and Elasticity of Single Stranded Nucleic Acids

Details The Effects of Stacking on the Configurations and Elasticity of Single Stranded Nucleic Acids The Effects of Stacking on the Configurations and Elasticity of Single Stranded Nucleic Acids

2004-07-21

arxiv.org/abs/q-bio/0407028v1

Phys. Rev. E 70 020902(R) (2004)

Biology

Quantitative Biology

Biomolecules

4 pages and 2 figures. Accepted in Phys. Rev. E Rapid Comm

Scientific paper

10.1103/PhysRevE.70.020902

Stacking interactions in single stranded nucleic acids give rise to configurations of an annealed rod-coil multiblock copolymer. Theoretical analysis identifies the resulting signatures for long homopolynucleotides: A non monotonous dependence of size on temperature, corresponding effects on cyclization and a plateau in the extension force law. Explicit numerical results for poly(dA) and poly(rU) are presented.

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