The effect of prolonged immobilization on diuresis and water intake in rats

Physics

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Scientific paper

Diuresis and water intake was determined in 20 male albino rats during 8 weeks of immobilization and in 10 rats in post-immobilization recovery phase. Increase of diuresis and water intake during the immobilization period have been observed. Neither changes in sodium and potassium excretion nor in Na/K ratio were found. As the immobilization of the rats did not cause any changes of their natural body position in relation to the direction of gravity forces, the effect of immobilization on diuresis and water intake could not be related to an ortostatic shift of blood or inhibition of the hypothalamo-hypophyseal antidiuretic system.

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