Surface modified silicon nanochannel for urea sensing

Details Surface modified silicon nanochannel for urea sensing Surface modified silicon nanochannel for urea sensing

2008-05-20

arxiv.org/abs/0805.3173v1

Physics

Biological Physics

5 pages, 6 figures, two-column format. Related papers can be found at nano.bu.edu

Scientific paper

10.1016/j.mee.2010.12.047

Silicon nanowires have been surface functionalized with the enzyme urease for biosensor applications to detect and quantify urea concentration. The device is nanofabricated from a silicon on insulator (SOI) wafer with a top down lithography approach. The differential conductance of silicon nanowires can be tuned for optimum performance using the source drain bias voltage, and is sensitive to urea at low concentration. The experimental results show a linear relationship between surface potential change and urea concentration in the range of 0.1 to 0.68 mM. The sensitivity of our devices shows high reproducibility with time and different measurement conditions. The nanowire urea biosensor offers the possibility of high quality, reusable enzyme sensor array integration with silicon based circuits.

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