Physics – Biological Physics
Scientific paper
2009-02-25
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 267 (2009) 983-988
Physics
Biological Physics
32 pages ; 8 figures
Scientific paper
10.1016/j.nimb.2009.02.016
Ion-induced cell killing has been reported to depend on the irradiation dose but also on the projectile parameters. In this paper we focus on two approaches developed and extensively used to predict cell survival in response to ion irradiation: the Local Effect Model and the Katz Model. These models are based on a track-structure description summarized in the concept of radial dose. This latter is sensitive to ion characteristics parameters and gives to both models the ability to predict some important radiobiological features for ion irradiations. Radial dose is however an average quantity, which does not include stochastic effects. These radiation-intrinsic effects are investigated by means of a Monte-Carlo simulation of dose deposition. We show that both models are not fully consistent with the nanometric and microscopic dose deposition statistics.
Beuve M.
Colliaux A.
Dabli D.
Dauvergne D.
Gervais B.
No associations
LandOfFree
Statistical effects of dose deposition in track-structure modelling of radiobiology efficiency does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Statistical effects of dose deposition in track-structure modelling of radiobiology efficiency, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Statistical effects of dose deposition in track-structure modelling of radiobiology efficiency will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-157485