SQUID-based microtesla MRI for in vivo relaxometry of the human brain

Details SQUID-based microtesla MRI for in vivo relaxometry of the human brain SQUID-based microtesla MRI for in vivo relaxometry of the human brain

2008-11-03

arxiv.org/abs/0811.0389v1

IEEE Trans. Appl. Supercond. 19:823-826, 2009

Physics

Medical Physics

To appear in Proceedings of 2008 Applied Superconductivity Conference

Scientific paper

10.1109/TASC.2009.2018764

SQUID-based MRI (magnetic resonance imaging) at microtesla fields has developed significantly over the past few years. Here we describe application of this method for magnetic relaxation measurements in the living human brain. We report values of the longitudinal relaxation time T1 for brain tissues, measured in vivo for the first time at microtesla fields. The experiments were performed at 46 microtesla field using a seven-channel SQUID system designed for microtesla MRI and MEG. Values of T1, measured for different tissues at this field, are found to be close (within 5%) to the corresponding values of the transverse relaxation time T2 at the same field. Implications of this result for imaging contrast in microtesla MRI are discussed.

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