Physics – Biological Physics
Scientific paper
2002-02-11
Biophysical Journal vol. 82 (2002) 3269-3276
Physics
Biological Physics
to appear in Biophysical Journal
Scientific paper
10.1016/S0006-3495(02)75668-3
Helix-coil transitions in poly-alanine molecules of length 10 are studied by multicanonical Monte Carlo simulations. The solvation effects are included by either a distance-dependent dielectric permittivity or by a term that is proportional to the solvent-accessible surface area of the peptide. We found a strong dependence of the characteristics of the helix-coil transition from the details of the solvation model.
Hansmann Ulrich H. E.
Peng Yejuan
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