Sodium chloride enhanced oligomerization of <Emphasis Type="SmallCaps">l</Emphasis>-glutamic acid in aqueous solution

Physics

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Scientific paper

The presence of NaCl was found to significantly enhance the formation of longer peptides in N,N′-carbonyldiimidazole induced oligomerization of l-glutamic acid in homogeneous aqueous solution. The enhancement was detected in the presence of as low as 0.01-M NaCl and the highest yield of longer oligomers was achieved in the presence of 1-M NaCl. The possible prebiotic relevance is discussed

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