Small Animal PET Imaging

Physics – Medical Physics

Scientific paper

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Scientific paper

As the methods and technology of positron emission tomography (PET) imaging have advanced, they have been applied not only to human clinical imaging, but to small research animals as well. Imaging small objects pushes the spatial resolution and sensitivity limits of current PET technology. We summarize the challenges presented in pushing these resolution limits without giving up sensitivity. Detector size is the current practical factor limiting resolution. Sensitivity is limited by detector characteristics and acquisition rate limits. Current scanners are capable of imaging small animals at the whole organ level. Very high resolution images can only be reached with large tracer doses and long data acquisition times.

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