Physics
Scientific paper
Mar 1999
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=1999njph....1....6o&link_type=abstract
New Journal of Physics, Volume 1, Issue 1, pp. 6 (1999).
Physics
21
Scientific paper
We elongated individual poly(ethylene-glycol) (PEG) molecules tethered at one end to an AFM cantilever. We observed the resistive force as a function of elongation in different solvents. In all cases the molecular response was found to be fully reversible and thus in thermodynamic equilibrium. In hexadecane the stretched PEG acts like an ideal entropy spring and can be well described as a freely jointed chain. In water we observed marked deviations in the transition region from entropic to enthalpic elasticity, indicating the deformation of a supra-structure within the polymer. An analysis based on elastically coupled Markovian two-level systems agrees well with recent ab initio calculations predicting that PEG in water forms a non-planar supra-structure which is stabilized by water bridges. We obtained a binding free energy of 3.0+/-0.3 kT.
Gaub Hermann E.
Oesterhelt F.
Rief Matthias
No associations
LandOfFree
Single molecule force spectroscopy by AFM indicates helical structure of poly(ethylene-glycol) in water does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Single molecule force spectroscopy by AFM indicates helical structure of poly(ethylene-glycol) in water, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Single molecule force spectroscopy by AFM indicates helical structure of poly(ethylene-glycol) in water will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-845198