Simultaneous measurement of quality factor and wavelength shift by phase shift microcavity ring down spectroscopy

Physics – Optics

Scientific paper

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Scientific paper

Optical resonant microcavities with ultra high quality factors are widely used for biosensing. Until now, the primary method of detection has been based upon tracking the resonant wavelength shift as a function of biodetection events. One of the sources of noise in all resonant-wavelength shift measurements is the noise due to intensity fluctuations of the laser source. An alternative approach is to track the change in the quality factor of the optical cavity by using phase shift cavity ring down spectroscopy, a technique which is insensitive to the intensity fluctuations of the laser source. Here, using biotinylated microtoroid resonant cavities, we show simultaneous measurement of the quality factor and the wavelength shift by using phase shift cavity ring down spectroscopy. These measurements were performed for disassociation phase of biotin-streptavidin reaction. We found that the disassociation curves are in good agreement with the previously published results. Hence, we demonstrate not only the application of phase shift cavity ring down spectroscopy to microcavities in the liquid phase but also simultaneous measurement of the quality factor and the wavelength shift for the microcavity biosensors in the application of kinetics measurements.

No associations

LandOfFree

Say what you really think

Search LandOfFree.com for scientists and scientific papers. Rate them and share your experience with other people.

Rating

Simultaneous measurement of quality factor and wavelength shift by phase shift microcavity ring down spectroscopy does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Simultaneous measurement of quality factor and wavelength shift by phase shift microcavity ring down spectroscopy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Simultaneous measurement of quality factor and wavelength shift by phase shift microcavity ring down spectroscopy will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFWR-SCP-O-165609

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.