Signal Propagation in Nonlinear Stochastic Gene Regulatory Networks

Details Signal Propagation in Nonlinear Stochastic Gene Regulatory Networks Signal Propagation in Nonlinear Stochastic Gene Regulatory Networks

2005-10-29

arxiv.org/abs/q-bio/0510055v1

Biology

Quantitative Biology

Molecular Networks

45 pages, 14 figures, Excerpts from this manuscript were presented at the 3rd International Conference on Pathways, Networks,

Scientific paper

The structure of a stochastic nonlinear gene regulatory network is uncovered by studying its response to input signal generators. Four applications are studied in detail: a nonlinear connection of two linear systems, the design of a logic pulse, a molecular amplifier and the interference of three signal generators in E2F1 regulatory element. The gene interactions are presented using molecular diagrams that have a precise mathematical structure and retain the biological meaning of the processes.

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