Sequence Dependence of Self-Interacting Random Chains

Details Sequence Dependence of Self-Interacting Random Chains Sequence Dependence of Self-Interacting Random Chains

1995-02-17

arxiv.org/abs/chem-ph/9502006v1

J. Phys. A28 (1995) 2121-2132

Physics

Chemical Physics

14 pages, uuencoded compressed postscript file

Scientific paper

10.1088/0305-4470/28/8/006

We study the thermodynamic behavior of the random chain model proposed by Iori, Marinari and Parisi, and how this depends on the actual sequence of interactions along the chain. The properties of randomly chosen sequences are compared to those of designed ones, obtained through a simulated annealing procedure in sequence space. We show that the transition to the folded phase takes place at a smaller strength of the quenched disorder for designed sequences. As a result, folding can be relatively fast for these sequences.

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