Sensorless adaptive optics for microscopy

Details Sensorless adaptive optics for microscopy Sensorless adaptive optics for microscopy

Feb 2011

adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2011spie.7931e..14j&link_type=abstract

MEMS Adaptive Optics V. Edited by Olivier, Scot S.; Bifano, Thomas G.; Kubby, Joel A. Proceedings of the SPIE, Volume 7931, p

Physics

Optics

Scientific paper

Most implementations of adaptive optics in microscopes have not employed a wavefront sensor, but have instead used sensorless aberration correction methods. In these systems, the aberration is determined indirectly through the optimisation of a quality metric, such as image intensity. We explain the principles behind this approach and show how efficient correction schemes can be developed using suitable mathematical models. In particular, we explain how the correct choice of aberration expansion enables the independent measurement of each aberration mode via a simple quadratic maximisation.

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