Self-organizing magnetic beads for biomedical applications

Details Self-organizing magnetic beads for biomedical applications Self-organizing magnetic beads for biomedical applications

2011-10-05

arxiv.org/abs/1110.0983v1

Physics

Biological Physics

Scientific paper

10.1016/j.jmmm.2011.09.034

In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows past microposts functionalized with antibodies for circulating tumor cells. Creating these microposts with interacting magnetic beads makes it possible to tune the geometry in size, position and shape. We developed a simulation tool that combines micromagnetics and discrete particle dynamics, in order to design micropost arrays made of interacting beads. The simulation takes into account the viscous drag of the blood flow, magnetostatic interactions between the magnetic beads and gradient forces from external aligned magnets. We developed a particle-particle particle-mesh method for effective computation of the magnetic force and torque acting on the particles.

Affiliated with

Also associated with

No associations

Rating

Self-organizing magnetic beads for biomedical applications does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Self-organizing magnetic beads for biomedical applications, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Self-organizing magnetic beads for biomedical applications will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-325365