Physics – Biological Physics
Scientific paper
2010-06-03
Phys. Rev. E 82, 031912 (2010)
Physics
Biological Physics
Final version published in Physical Review E
Scientific paper
10.1103/PhysRevE.82.031912
Ribosome is a molecular machine that moves on a mRNA track while, simultaneously, polymerizing a protein using the mRNA also as the corresponding template. We define, and analytically calculate, two different measures of the efficiency of this machine. However, we arugue that its performance is evaluated better in terms of the translational fidelity and the speed with which it polymerizes a protein. We define both these quantities and calculate these analytically. Fidelity is a measure of the quality of the products while the total quantity of products synthesized in a given interval depends on the speed of polymerization. We show that for synthesizing a large quantity of proteins, it is not necessary to sacrifice the quality. We also explore the effects of the quality control mechanism on the strength of mechano-chemical coupling. We suggest experiments for testing some of the ideas presented here.
Chowdhury Debashish
Sharma Ajeet K.
No associations
LandOfFree
Quality control by a mobile molecular workshop: quality versus quantity does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Quality control by a mobile molecular workshop: quality versus quantity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quality control by a mobile molecular workshop: quality versus quantity will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-513660