Phase Transition Induced Fission in Lipid Vesicles

Details Phase Transition Induced Fission in Lipid Vesicles Phase Transition Induced Fission in Lipid Vesicles

2010-05-24

arxiv.org/abs/1005.4440v1

Biophysical Chemistry 143 (2009) 106-109

Physics

Biological Physics

Scientific paper

In this work we demonstrate how the first order phase transition in giant unilamellar vesicles (GUVs) can function as a trigger for membrane fission. When driven through their gel-fluid phase transition GUVs exhibit budding or pearl formation. These buds remain connected to the mother vesicle presumably by a small neck. Cooling these vesicles from the fluid phase (T>Tm) through the phase transition into the gel state (T

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