Optimal Control of Evolutionary Dynamics

Details Optimal Control of Evolutionary Dynamics Optimal Control of Evolutionary Dynamics

2008-06-13

arxiv.org/abs/0806.2331v1

Biology

Quantitative Biology

Molecular Networks

Extends "Mutagenic evidence for the optimal control of evolutionary dynamics" (accepted, Physical Review Letters)

Scientific paper

Elucidating the fitness measures optimized during the evolution of complex biological systems is a major challenge in evolutionary theory. We present experimental evidence and an analytical framework demonstrating how biochemical networks exploit optimal control strategies in their evolutionary dynamics. Optimal control theory explains a striking pattern of extremization in the redox potentials of electron transport proteins, assuming only that their fitness measure is a control objective functional with bounded controls.

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