On the codon assignment of chain termination signals and the minimization of the effects of frameshift mutations

Details On the codon assignment of chain termination signals and the minimization of the effects of frameshift mutations On the codon assignment of chain termination signals and the minimization of the effects of frameshift mutations

1997-06-12

arxiv.org/abs/physics/9706019v1

Physics

Biological Physics

4 pages, LaTeX, two tables available from authors

Scientific paper

It has been suggested that the minimization of the probability for lethal
mutations is a major constraint shaping the genetic code, with the finding that
the genetic code is highly protective against transition mutations. Here, we
show that recent data on polymerase-induced frameshifts provide a rationale for
the codon assignment of chain termination signals (CTS).

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