Multiple Thresholds in a Model System of Noisy Ion Channels

Details Multiple Thresholds in a Model System of Noisy Ion Channels Multiple Thresholds in a Model System of Noisy Ion Channels

2006-02-23

arxiv.org/abs/physics/0602158v4

Phys. Rev. E 74, 041913 (2006)

Physics

Biological Physics

REVTeX 4, 5 pages, 4 figures; added paragraph

Scientific paper

10.1103/PhysRevE.74.041913

Voltage-activated ion channels vary randomly between open and closed states, influenced by the membrane potential and other factors. Signal transduction is enhanced by noise in a simple ion channel model. The enhancement occurs in a finite range of signals; the range can be extended using populations of channels. The range increases more rapidly in multiple-threshold channel populations than in single-threshold populations. The diversity of ion channels may thus be present as a strategy to reduce the metabolic costs of handling a broad class of electrochemical signals.

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