Model Channel Ion Currents in NaCl - SPC/E Solution with Applied-Field Molecular Dynamics

Details Model Channel Ion Currents in NaCl - SPC/E Solution with Applied-Field Molecular Dynamics Model Channel Ion Currents in NaCl - SPC/E Solution with Applied-Field Molecular Dynamics

2001-10-04

arxiv.org/abs/physics/0110016v1

Physics

Biological Physics

Accepted for publication in Biophysical Journal

Scientific paper

10.1016/S0006-3495(01)75946-2

Using periodic boundary conditions and a constant applied field, we have simulated current flow through an 8.125 Angstrom internal diameter, rigid, atomistic channel with polar walls in a rigid membrane using explicit ions and SPC/E water. Channel and bath currents were computed from ten 10-ns trajectories for each of 10 different conditions of concentration and applied voltage. An electric field was applied uniformly throughout the system to all mobile atoms. On average, the resultant net electric field falls primarily across the membrane channel, as expected for two conductive baths separated by a membrane capacitance. The channel is rarely occupied by more than one ion. Current-voltage relations are concentration-dependent and superlinear at high concentrations.

Affiliated with

Also associated with

No associations

Rating

Model Channel Ion Currents in NaCl - SPC/E Solution with Applied-Field Molecular Dynamics does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Model Channel Ion Currents in NaCl - SPC/E Solution with Applied-Field Molecular Dynamics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Model Channel Ion Currents in NaCl - SPC/E Solution with Applied-Field Molecular Dynamics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-417463