Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly

Details Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly Melting Transition of Directly-Linked Gold Nanoparticle DNA Assembly

2005-03-10

arxiv.org/abs/physics/0503090v1

Physica A, 350 (2005) 89-94

Physics

Biological Physics

6 pages, 4 figures, Physica A (2005) to appear

Scientific paper

10.1016/j.physa.2005.01.013

DNA melting and hybridization is a fundamental biological process as well as a crucial step in many modern biotechnology applications. DNA confined on surfaces exhibits different behavior from that in free solutions. The system of DNA-capped gold nanoparticles exhibits unique phase transitions and represents a new class of complex fluids. Depending on the sequence of the DNA, particles can be linked to each other through direct complementary DNA sequences or via a ``linker'' DNA whose sequence is complementary to the sequence attached to the gold nanoparticles. We observed different melting transitions for these two distinct systems.

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