Mapping cellular magnesium using X-ray microfluorescence and atomic force microscopy

Details Mapping cellular magnesium using X-ray microfluorescence and atomic force microscopy Mapping cellular magnesium using X-ray microfluorescence and atomic force microscopy

2010-07-10

arxiv.org/abs/1007.1744v1

Biology

Quantitative Biology

Cell Behavior

9 pages, 2 figures

Scientific paper

Magnesium is the most abundant intracellular divalent cation. We present an innovative experimental approach to localizing intracellular magnesium that combines elemental and morphological information from individual cells with high-resolution spatial information. Integration of information from scanning fluorescence X-ray microscopy with information from atomic force microscopy was used to generate a magnesium concentration map and to determine the X-ray linear absorption coefficient map within a whole dehydrated mammary epithelial cell.

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