Biology – Quantitative Biology – Tissues and Organs
Scientific paper
Jan 2000
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2000aipc..504..295t&link_type=abstract
SPACE TECHNOLOGY AND APPLICATIONS INTERNATIONAL FORUM - 2000. AIP Conference Proceedings, Volume 504, pp. 295-299 (2000).
Biology
Quantitative Biology
Tissues and Organs
Mechanical Properties Of Tissues And Organs, Clinical Imaging Studies, Instrumentation
Scientific paper
Magnetic resonance microscopy (MRM) may be very useful in the ex vivo study of osteoporosis as non destructive technique able to provide three dimensional information of the bone architecture. However, the trabecular width appears larger in conventional MR images, as the susceptibility effect at the bone-marrow interface causes signal dephasing. Such an effect can be minimized if the echo-time (TE) or voxel size are reduced. The purpose of our research was the development of new MRM techniques that have a potential role in the characterization of trabecular bone architecture. In this study we describe the use of short-TE projection reconstruction MRM for the study of normal and osteoporotic bone explants. This method promises to be more accurate than conventional MRM in the analysis of trabecular bone. In vivo projection reconstruction MR imaging could be applied to evaluate bone architecture and bone quality evolution after space flight exposure. .
Cova Maria
Jellúš Vladimír
Pozzi-Mucelli Roberto S.
Szomolanyi Pavol
Toffanin Renato
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