Biology – Quantitative Biology – Quantitative Methods
Scientific paper
2004-01-09
Biology
Quantitative Biology
Quantitative Methods
Scientific paper
10.1016/j.physd.2003.11.012
A lattice-gas cellular automaton (LGCA) model is used to simulate rippling and aggregation in myxobacteria. An efficient way of representing cells of different cell size, shape and orientation is presented that may be easily extended to model later stages of fruiting body formation. This LGCA model is designed to investigate whether a refractory period, a minimum response time, a maximum oscillation period and non-linear dependence of reversals of cells on C-factor are necessary assumptions for rippling. It is shown that a refractory period of 2-3 minutes, a minimum response time of up to 1 minute and no maximum oscillation period best reproduce rippling in the experiments of {\it Myxoccoccus xanthus}. Non-linear dependence of reversals on C-factor is critical at high cell density. Quantitative simulations demonstrate that the increase in wavelength of ripples when a culture is diluted with non-signaling cells can be explained entirely by the decreased density of C-signaling cells. This result further supports the hypothesis that levels of C-signaling quantitatively depend on and modulate cell density. Analysis of the interpenetrating high density waves shows the presence of a phase shift analogous to the phase shift of interpenetrating solitons. Finally, a model for swarming, aggregation and early fruiting body formation is presented.
Alber Mark S.
Jiang Yi
Kiskowski Maria A.
No associations
LandOfFree
Lattice gas cellular automata model for rippling and aggregation in myxobacteria does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Lattice gas cellular automata model for rippling and aggregation in myxobacteria, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lattice gas cellular automata model for rippling and aggregation in myxobacteria will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-688789