Large attractors in cooperative bi-quadratic Boolean networks. Part II

Details Large attractors in cooperative bi-quadratic Boolean networks. Part II Large attractors in cooperative bi-quadratic Boolean networks. Part II

2008-01-29

arxiv.org/abs/0801.4556v1

Biology

Quantitative Biology

Molecular Networks

14 pages

Scientific paper

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by simultaneous updating at discrete time steps. Of particular importance for biological applications are networks in which the indegree for each variable is bounded by a fixed constant, as was stressed by Kauffman in his original papers. An important question is which conditions on the network topology can rule out exponentially long periodic orbits in the system. In this paper we consider cooperative systems, i.e. systems with positive feedback interconnections among all variables, which in a continuous setting guarantees a very stable dynamics. In Part I of this paper we presented a construction that shows that for an arbitrary constant 0

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