Large attractors in cooperative bi-quadratic Boolean networks. Part I

Details Large attractors in cooperative bi-quadratic Boolean networks. Part I Large attractors in cooperative bi-quadratic Boolean networks. Part I

2007-11-18

arxiv.org/abs/0711.2799v2

Biology

Quantitative Biology

Molecular Networks

13 pages, 2 figures resubmission with additional references

Scientific paper

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by simultaneous updating at discrete time steps. Of particular importance for biological applications are networks in which the indegree for each variable is bounded by a fixed constant, as was stressed by Kauffman in his original papers. An important question is which conditions on the network topology can rule out exponentially long periodic orbits in the system. In this paper, we consider systems with positive feedback interconnections among all variables (known as cooperative systems), which in a continuous setting guarantees a very stable dynamics. We show that for an arbitrary constant 0

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