Label-free electrical quantification of the dielectrophoretic response of DNA

Details Label-free electrical quantification of the dielectrophoretic response of DNA Label-free electrical quantification of the dielectrophoretic response of DNA

2009-01-19

arxiv.org/abs/0901.2827v1

PMC Biophysics 2008, 1:4

Physics

Biological Physics

12 pages, 7 figures

Scientific paper

10.1186/1757-5036-1-4

A purely electrical sensing scheme is presented that determines the concentration of macromolecules in solution by measuring the capacitance between planar microelectrodes. Concentrations of DNA in the ng/mL range have been used in samples of 1 microL volume. The method has been applied to the characterisation of the dielectrophoretic response of DNA without the need for any chemical modifications. The influence of electrical parameters like duty cycle, voltage and frequency has been investigated. The results are in good agreement with data from dielectrophoretic studies on fluorescently labelled DNA. Extension of the method down to the single molecule level appears feasible.

Affiliated with

Also associated with

No associations

Rating

Label-free electrical quantification of the dielectrophoretic response of DNA does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Label-free electrical quantification of the dielectrophoretic response of DNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Label-free electrical quantification of the dielectrophoretic response of DNA will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-566639