Kinetics of viral self-assembly: the role of ss RNA antenna

Details Kinetics of viral self-assembly: the role of ss RNA antenna Kinetics of viral self-assembly: the role of ss RNA antenna

2006-11-20

arxiv.org/abs/q-bio/0611066v4

Phys. Rev. E 75, 051901 (2007)

Biology

Quantitative Biology

Biomolecules

4 pages, 3 figures, several experiments are proposed, a new idea of experiment is added

Scientific paper

10.1103/PhysRevE.75.051901

A big class of viruses self-assemble from a large number of identical capsid proteins with long flexible N-terminal tails and ss RNA. We study the role of the strong Coulomb interaction of positive N-terminal tails with ss RNA in the kinetics of the in vitro virus self-assembly. Capsid proteins stick to unassembled chain of ss RNA (which we call "antenna") and slide on it towards the assembly site. We show that at excess of capsid proteins such one-dimensional diffusion accelerates self-assembly more than ten times. On the other hand at excess of ss RNA, antenna slows self-assembly down. Several experiments are proposed to verify the role of ss RNA antenna.

Affiliated with

Also associated with

No associations

Rating

Kinetics of viral self-assembly: the role of ss RNA antenna does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Kinetics of viral self-assembly: the role of ss RNA antenna, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Kinetics of viral self-assembly: the role of ss RNA antenna will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-339069