Biology – Quantitative Biology – Molecular Networks
Scientific paper
2010-10-12
Biology
Quantitative Biology
Molecular Networks
12 pages, 9 figures
Scientific paper
It is shown, by means of numerical simulations, that intercellular spiral waves of calcium can be initiated in a network of coupled cells as a result of a de-synchronization between Ca2+ oscillations in two domains. No artificial heterogeneities need to be imposed to the system for spontaneous formation of spiral waves. The de-synchronization occurs near the interface of the stimulated region (which acts as a pacemaker) and propagates over the entire network. We also find the outcome of the collision of two spiral waves.
Kepseu Wilfred D.
Sakaguchi Hidetsugu
Woafo Paul
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