Influence of fluctuations in actin structure on myosin V step size

Details Influence of fluctuations in actin structure on myosin V step size Influence of fluctuations in actin structure on myosin V step size

2005-09-16

arxiv.org/abs/physics/0509148v1

J. Chem. Inf. Model. 45, 1672-1675 (2005)

Physics

Biological Physics

5 pages, 4 figures, to appear in J. Chem. Inf. Model

Scientific paper

10.1021/ci050182m

We study the influence of disorder in the helical actin structure on the
myosin V step size, predicted from the elastic lever arm model. We show that
fluctuations of +-5 degrees per actin subunit, as proposed by Egelman et al.,
significantly alter the distribution of step sizes and improve the agreement
with experimental data.

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