Physics – Medical Physics
Scientific paper
Apr 2006
adsabs.harvard.edu/cgi-bin/nph-data_query?bibcode=2006apsp.conf..720m&link_type=abstract
ASTROPARTICLE, PARTICLE AND SPACE PHYSICS, DETECTORS AND MEDICAL PHYSICS APPLICATIONS . Proceedings of the 9th Conference . Held
Physics
Medical Physics
Scientific paper
Imaging techniques with radionuclides provide very sensitive measures of a wide range of specific processes underying disease in the body. Detection of very small tumors with high specificity is therefore possible but the tecnique requires both high spatial resolution and high sensitivity.
We present the first simulations, performed by means of GEANT4 code, of breast tumors, imaged by different configurations of a compact discrete gamma camera, in order to optimize the performances of dedicated detectors for these tasks. Simulated planar images from 6 to 10 mm diameter tumors, placed at 5 mm from the collimator, were generated for NaI scintillator pixel sizes of 1.0×1.0 and 1.2×1.2 mm2, hexagonal hole Pb collimators with hole size of 1.5 and 1.9 mm. The generated photons have been sampled by two modelled Hamamatsu H8500 and H9500 PMT. Tumor to background uptake ratio from 1:6 to 1:12 has been considered.
The preliminary results in terms of spatial resolution and SNR show a slightly better performance of the high efficiency collimator, larger crystal size and H9500 combination.
Cinti Maria N.
Cisbani Evaristo
Colilli S.
Cusanno F.
de Vincentis G.
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